M. R. Harnden, R. L. Jarvest
1985
Citations
0
Influential Citations
51
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Alkylation of 2-amino-6-chloropurine with 5-(2-bromoethyl)-2,2-dimethyl-1,3-dioxan ( 7 ) and subsequent acid hydrolysis provides an improved procedure for synthesis of the antiviral acyclonucleoside 9-(4-hydroxy-3-hydroxymethylbut-1-yl) guanine ( 3 ).