Matthew Badland, Carol A. Bains, Roger M. Howard
Apr 21, 2010
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Influential Citations
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Journal
Tetrahedron-asymmetry
Abstract
An improved synthesis of (1R,3S)-3-[(tert-butoxycarbonyl)amino]cyclohexanecarboxylic acid from 3-aminobenzoic acid is described utilising milder and more selective conditions. Both a classical salt resolution and an enzymatic approach have been shown to give the desired compound in high selectivity.