Ashty Saleh, F. Compernolle, G. Janssen
1995
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0
Influential Citations
2
Citations
Journal
Nucleosides, Nucleotides & Nucleic Acids
Abstract
Abstract We report an improved synthesis of N 6-(6-aminohexyl)FAD (1) using an efficient one-pot conversion of inosine to the N-trifluoroacetyl protected N 6-(6-aminohexyl)adenosine 3. The 5′-O-phosphorylated AMP derivative 4, activated as the imidazolide, was coupled with commercial sodium riboflavin phosphate by using 18-crown-6 in DMF.