T. Asako, K. Hiraga, T. Miki
Jan 25, 1973
Citations
0
Influential Citations
9
Citations
Journal
Chemical & Pharmaceutical Bulletin
Abstract
17α-Hydroxy-3-methoxy-8, 14-secoestra-1, 3, 5 (10), 9-tetraen-14-one (IIa) which is an intermediate for the total synthesis of estrogens has been optically resolved. The isomer which has unnatural configuration at C-13 has been converted to estrapentaene 3-methyl ether (IVa) via the 9, 14-epoxy intermediates (XI, XII, XIII, XV).