Fabienne Hoffmann-Emery, R. Jakob‐Roetne, A. Flohr
Nov 18, 2009
Citations
0
Influential Citations
15
Citations
Journal
Tetrahedron Letters
Abstract
An improved synthesis of (S)-7-amino-5H,7H-dibenzo[b,d]azepin-6-one (1), involving a selective crystallization of epimeric menthylcarbamates for the resolution step followed by simultaneous cleavage of the carbamate and the lactam protecting group is described. Epimerization conditions of the undesired epimer have also been determined.