Robert J. A. Ramirez, Levon Karamanukyan, Steven Ortiz
Feb 3, 1997
Citations
1
Influential Citations
23
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Enterobactin, the cyclic trimer of N-(2,3-dihydroxybenzoyl)-L-serine has been efficiently prepared. A simple and high yield procedure has been developed for construction of N-protected serine trilactone as the key intermediate: methyl N-trityl-L-serinate and 2,2-dibutyl-1,3,2-dioxastannolane were refluxed in xylene to produce the triolide as the only lactone product in 85% yield.