D. H. Kim, Sang J. Chung
Aug 3, 1995
Citations
0
Influential Citations
13
Citations
Journal
Bioorganic & Medicinal Chemistry Letters
Abstract
Abstract 2-Benzyl-3,4-epithiobutanoic acid was designed and synthesized as a pseudomechanism-based inactivator for carboxypeptidase A. Designing rationale, synthesis of racemic 2-benzyl-3,4-epithiobutanoic acid having (2 S ,3 S )- and (2 R ,3 R )-configurations, and inhibitory kinetic parameters and their implications are reported.