T. Moriya, Shinichiro Yoneda, Keita Kawana
Sep 13, 2012
Citations
0
Influential Citations
24
Citations
Journal
Organic letters
Abstract
The combination of 1,1,3,3-tetramethyldisiloxane (TMDS) and trimethylbromosilane (Me(3)SiBr) with a catalytic amount of indium bromide (InBr(3)) undertook direct bromination of carboxylic acids, which produced the corresponding alkyl bromides in good to excellent yields. The reducing system was tolerant to several functional groups.