Lingjie Meng, Qing-lan Guo, Yufeng Liu
Apr 29, 2017
Citations
4
Influential Citations
41
Citations
Quality indicators
Journal
Acta Pharmaceutica Sinica. B
Abstract
Six new indole alkaloid sulfonic acids (1–6), together with two analogues (7 and 8) that were previously reported as synthetic products, were isolated from an aqueous extract of the Isatis indigotica root. Their structures including the absolute configurations were determined by spectroscopic data analysis, combined with enzyme hydrolysis and comparison of experimental circular dichroism and calculated electronic circular dichroism spectra. In the preliminary assay, compounds 2 and 4 showed antiviral activity against Coxsackie virus B3 and influenza virus A/Hanfang/359/95 (H3N2), respectively.