J. Wanka, L. Jones, P. Wood
May 1, 1964
Citations
0
Influential Citations
52
Citations
Journal
Annals of the Rheumatic Diseases
Abstract
Indomethacin (l-(p-chlorbenzoyl)-5-methoxy-2methylindole-3-acetic acid) (Fig. 1) is a compound which has been shown to have anti-inflammatory and antipyretic action in experimental animals (Hodgkinson, 1963). Enthusiastic but largely uncontrolled studies of its action in rheumatoid arthritis and other disorders have been reported (see Proceedings of the American Rheumatism Association, 1963) and more recently reports of its therapeutic value have been published in Great Britain (Hart and Boardman, 1963). This paper reports experiences with this drug over the last year in the treatment of rheumatoid arthritis and other conditions. The study was conducted in three parts: