R. Matagne
Mar 1, 1969
Citations
0
Influential Citations
18
Citations
Journal
Mutation research
Abstract
Abstract After transformation into active compound(s) (probably diepoxybutane) the L -, D - and meso -isomers of threitol-1,4-bismethanesulfonate can induced chromosomal aberrations in barley and onion root-tips. Quantitative differences are found between the effects of the isomers ( L > D > meso ), but the 3 forms induce similar qualitative effects as judged by various criteria: the types of aberrations; the location of breaks in heterochromatic or euchromatic segments of the genome in relation to the sampling time; and the relative proportions of breaks in mediocentric chromosomes and satellite chromosomes of onion. The mutagenic activity of the 3 isomers was investigated in Arabidopsis thaliana : it was found that quantitative differences also exist when the treatment conditions allow chemical transformation and subsequent mutagenic effects.