J. Reihill, B. Malcomson, A. Bertelsen
Feb 1, 2016
Citations
0
Influential Citations
30
Citations
Journal
British Journal of Pharmacology
Abstract
NF‐κB‐driven inflammation is negatively regulated by the zinc finger protein A20. Gibberellic acid (GA3) is a plant‐derived diterpenoid with documented anti‐inflammatory activity, which is reported to induce A20‐like zinc finger proteins in plants. Here, we sought to investigate the anti‐inflammatory effect of GA3 in airway epithelial cells and determine if the anti‐inflammatory action relates to A20 induction.