V. V. Tkachenko, E. Muravyova, S. Desenko
Dec 17, 2014
Citations
0
Influential Citations
12
Citations
Journal
Beilstein Journal of Organic Chemistry
Abstract
Summary The switchable three-component reactions of 5-amino-3-methylisoxazole, salicylaldehyde and N-aryl-3-oxobutanamides under different conditions were studied and discussed. The unexpected influence of the aryl substituent in N-aryl-3-oxobutanamides on the behavior of the reaction was discovered. The key influence of ultrasonication and Lewis acid catalysts led to an established protocol to selectively obtain two or three types of heterocyclic scaffolds depending on the substituent in the N-aryl moiety.