M. Schuderer, Martin R. Schneider
1987
Citations
0
Influential Citations
6
Citations
Journal
Archiv der Pharmazie
Abstract
The phenolic hydroxy groups of 1,1‐bis‐(4‐hydroxyphenyl)‐2‐phenylbut‐1‐ene (1) were converted to esters of different chain length and degree of halogen substitution, and to carbamate, imidoester and ether derivatives. Most of the products maintain the affinity to the estrogen receptor. The acetate 2 has a better antitumor potency than 1.