L. Mazur, A. Kozioł, J. Krzywda
Feb 28, 2003
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Journal
Journal of Molecular Structure
Abstract
Abstract Three solvates of 5-(morpholinemethyl)-3-[(4-chlorobenzylidene)amino]-2-oxazolidinone ( I ) have been prepared and their solid-state structures analysed. In the semihydrate crystals ( Ia ), the base is observed in the usual overall extended conformation. The dihydrate ( Ib ) and formamide complex ( Ic ) are isostructural and share the same general packing of base molecules, which adopt a bent conformation with helical catemers of solvent; the differences are mainly in the number of host–guest interactions. Both crystals were formed exclusively during the deprotonation of I HCl in polar solvents. In crystal lattices, the 5-(morpholinemethyl)-3-(aminomethylene)-2-oxazolidinone fragment of I is a principal synthon in intermolecular host–host and host–guest contacts. It is usually an acceptor in the Y–H⋯O and/or Y–H⋯N [Y=O, N, C] bonds, and a chelating donor to the C–H⋯X [X=O, Cl, Cl − ] bonds.