W. Sziegoleit, A. Ehrhardt, P. Haase
1984
Citations
0
Influential Citations
3
Citations
Quality indicators
Journal
Biomedica biochimica acta
Abstract
Clinical-pharmacological investigations on interactions between cyclo-oxygenase inhibitors and beta-adrenoceptor blocking agents continuing, indometacin and acetylsalicylic acid (ASA) were added to a monotherapy of talinolol in two groups of hypertensive outpatients. Both added drugs reduced slightly the blood pressure lowering effect of talinolol, but did not alter its negative chronotropic effect. Indometacin abolished a talinolol-induced increase in serum triglycerides and caused a small decrease in serum cholesterol. ASA diminished slightly blood glucose. Probably the observed interactions and side effects are not important practically.