G. Schmeer, S. Riembauer, J. Barthel
Dec 1, 1990
Citations
0
Influential Citations
9
Citations
Journal
Journal of Solution Chemistry
Abstract
The rate constants of the alkaline hydrolysis of 2-methylpropionic acid ethyl ester, α-hydroxy, α-bromo, α-cyano, and α-nitro-2-methylpropionic acid ethyl ester have been measured in water between 5°C and 45°C with the help of an appropriate conductance bridge developed in our laboratory. The influence of the polar substituents on the rate constant, a powerful probe for discussing two-particle interactions in solutions, is characterized by an intramolecular structure parameter of the activated complex and a dielectric parameter of its surroundings. The dependence of the reaction rate on the structure parameter is compared to that of substituted acetic acid derivatives. The smaller dielectric parameter of 2-methylpropionic acid esters reveals the increasing hydrophobic solvation in comparison to acetic acid derivatives.