H. Kawahara, G. Drew, MJ Christie
Jul 1, 2011
Citations
3
Influential Citations
64
Citations
Quality indicators
Journal
British Journal of Pharmacology
Abstract
BACKGROUND AND PURPOSE While arachidonyl ethanolamine (anandamide) produces pharmacological effects mediated by cannabinoid CB1 receptors, it is also an agonist at the transient receptor potential vanilloid type 1 (TRPV1) ion channel. This study examined the cellular actions of anandamide in the midbrain periaqueductal grey (PAG), a region implicated in the analgesic actions of cannabinoids, and which expresses both CB1 receptors and TRPV1.