E. J. Oliver, R. Mortlock
Jul 7, 1969
Citations
0
Influential Citations
6
Citations
Journal
Biochemical and biophysical research communications
Abstract
Abstract Dithiothreitol was found to be a competitive inhibitor for a purified L-fucose isomerase from Aerobacter aerogenes , inhibiting enzyme activity for the isomerization of both L-fucose and D-arabinose. The kinetics of inhibition showed that the oxidized form was the more potent inhibitor. The Ki for both sugars was the same. Dithioerythitol and certain polyalcoholic sugars also appeared to function as competitive inhibitors of the enzyme.