A. Mccoubrey
Nov 1, 1959
Citations
0
Influential Citations
7
Citations
Journal
Biochemical Pharmacology
Abstract
Abstract Alkyloxy with or without additional alkyl or hydroxy substituents in the benzene ring considerably enhanced the weak anti-monoamine oxidase activity of 1-phenylethylamine. 1-(3- n -Hexyloxy-4-hydroxy-5- n -propylphenyl) ethylamine had good inhibitory power at 10 −4 M at pH 6.8, but the activity declined on the alkaline side of neutrality. It antagonized the prolongation of barbiturate narcosis in mice due to reserpine.