J. Ryu, Hanna Ahn, Hwa Jin Lee
Jun 1, 2003
Citations
2
Influential Citations
40
Citations
Quality indicators
Journal
Fitoterapia
Abstract
The ethyl acetate soluble fraction of Broussonetia kazinoki at 50 microg/ml showed a significant inhibition (78.2%) of nitric oxide (NO) in lipopolysaccharide activated macrophages. Kazinol B, an isoprenylated flavan, was identified as the active principle. It inhibits the NO synthesis with an IC(50) of 21.6 microM.