L. K. Gavrin, N. Green, Yonghan Hu
Dec 1, 2005
Citations
0
Influential Citations
47
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
The synthesis and structure-activity studies of a series of 6-substituted-4-anilino-[1,7]-naphthyridine-3-carbonitriles as inhibitors of Tpl2 kinase are described. The early exploratory work described here may lead to the discovery of compounds with significant therapeutic potential for treating rheumatoid arthritis and other inflammatory diseases.