K. Yamada, Y. Kobayashi, H. Fujihara
May 15, 1998
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0
Influential Citations
4
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Quality indicators
Journal
Biological & pharmaceutical bulletin
Abstract
Intraperitoneal administration of 2,5-dimethylpyrazine (2,5-DMP) was found to inhibit oxytocin- and prostaglandin F2alpha-induced tetanic uterine contractions in normal or pregnant female rats. This suggests that 2,5-DMP may be used as a countercontraction agent or relaxant for preventing oxytocic agent-induced medical accident including uterine rupture or pressure death of the fetus due to uterine contractions.