E. V. Sadchikova, V. Mokrushin
Sep 14, 2014
Citations
0
Influential Citations
4
Citations
Journal
Chemistry of Heterocyclic Compounds
Abstract
We studied the reactivity of diethyl 4-aminoimidazo[5,1-с][1,2,4]triazine-3,8-dicarboxylate in reactions with nucleophiles and demonstrated the possibility of selective formation of monoamides by interaction with primary and secondary aliphatic amines. It was determined that the carbon atom at position 4 of imidazo[1,5-с][1,2,4]triazine system underwent nucleophilic attack, enabling the synthesis of imidazo-[1',5':3,4][1,2,4]triazino[5,6-b][1,5]benzoxazepines and imidazo[1',5':3,4][1,2,4]triazino[5,6-b][1,5]benzo- diazepines, as well as (pyrazol-4-ylidenehydrazino)imidazoles, depending on the bisnucleophile used.