G. Meiramov, A. P. Andreeva, K. Kohnert
Jun 1, 1997
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Journal
Bulletin of Experimental Biology and Medicine
Abstract
Repeated administration of xanthurenic acid to experimental animals completely eliminates insulin stores in pancreatic B cells and attenuates normalization of blood glucose level in the glucose tolerance test. Xanthurenic acid inhibits insulin secretion by isolated pancreatic islets and decreases zinc-specific luminescent reaction in B cells.