Chunshen Zhao, Fei Li, Shuo Yang
Jun 27, 2018
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Journal
Chemistry of Heterocyclic Compounds
Abstract
3- and 8-Iodoimidazo[1,2-a]pyridines were synthesized from imidazo[1,2-a]pyridine under different substitution conditions. The molecular electrostatic potential calculations were performed to investigate the chemoselectivity of the substitution reaction. The molecular structures of the target compounds were characterized by single crystal X-ray diffraction analysis.