Cunde Wang, Zhenjie Su, Shanlu Wang
Apr 2, 2020
Citations
0
Influential Citations
3
Citations
Journal
Synlett
Abstract
Abstract An iodine-catalyzed [3+2]-cycloaddition reaction of substituted benzylidenemalononitriles and ethyl glycinate hydrochloride in DMF has been developed for the synthesis of 5-amino-1H-pyrrole-2-carboxylates. This efficient method provides access to a variety of structurally diverse pyrrole-2-carboxylate derivatives. The structure of a typical product was confirmed by X-ray crystallography.