Yujing Guo, Shuai Lu, Lu-Lu Tian
Jan 5, 2018
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Influential Citations
91
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Journal
The Journal of organic chemistry
Abstract
Novel iodine-induced sulfonylation and sulfenylation of imidazopyridines have been described using sodium sulfinates as the sulfur source. This strategy enables highly selective difunctionalization of imidazo[1,2-a]pyridine to access sulfones and sulfides in good yields. A wide range of substrates and functional groups were well-tolerated under optimized conditions. Moreover, control experiments have been conducted, indicating a radical pathway involved in the reaction mechanisms.