M. Mahdavi, Mahsa Khoshbakht, Mina Saeedi
Jan 7, 2016
Citations
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Influential Citations
8
Citations
Journal
Synthesis
Abstract
Abstract The reaction between N,2-diarylhydrazinecarbothioamide (generated from arylhydrazines and aryl isothiocyanates) and malononitrile in the presence of iodine/triethylamine in N,N-dimethylformamide at 80 °C afforded novel pyrazoles, 5-amino-1-aryl-3-(arylamino)-1H-pyrazole-4-carbonitriles, in good yields. In this strategy, iodine served as a versatile desulfurizing agent, efficiently promoting the cyclization reaction.