G. Sabitha, G. K. Reddy, M. Rajkumar
Sep 29, 2003
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0
Influential Citations
20
Citations
Journal
Tetrahedron Letters
Abstract
The synthesis of multifunctionalized tetrahydropyranones has been achieved at room temperature with iodotrimethylsilane by a tandem Knoevenagel condensation of aldehydes with aldol adducts prepared from β-keto esters and aldehydes, followed by a Michael reaction. The reactions are highly diastereoselective affording a single isomer in high yields.