Joseph L. Scott
May 1, 1962
Citations
0
Influential Citations
3
Citations
Journal
Poultry Science
Abstract
Abstract The results of recent investigations concerning the metabolism of epinephrine by mammals has encouraged the initiation of similar studies upon the chicken and other lower forms of vertebrates. The role of two enzymes,o-methyl-transferase and monoamine oxidase, has been clarified in the cat (Kirschner, 1960) and in the mouse and rat (Alexrod, 1960). The evidence from radioactivity recovery experiments performed upon 6–7 week old Leghorn chickens is reported as an initial indication that a monoamine oxidase is involved in the inactivation of epinephrine in this animal. Nine Leghorn chickens were divided into three groups and treated by intraperitoneal injections as follows: 1) Experiment 1, each of three birds received 0.7 mg. DL-epinephrine-D-bitartrate-C14,3 in water, 2) Experiment 2, each of three birds received 1.0 mg. DL-epinephrine-D-bitartrate (methyl C14) 3 in water, and 3) Experiment 3, each of three birds received 50 mg. of iproniazid and four hours later (1.0 mg. of DL-epinephrine-D-bitartrate …