N. Furukawa, S. Ogawa, T. Kawai
1983
Citations
0
Influential Citations
13
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Both the sulfinyl and sulfonyl groups directly bound to 2 or 4 position in pyridine were readily displaced by several nucleophiles such as RO- and RS-. The facility of the leaving groups is RSO2⋍RSO>Br⋍>>RS (R:alyl or benzyl). The ipso-substituion could be applied for the synthesis of new type of 2,6-disubstituted macrocycles containing both carbonoxygen and carbon-sulfur bridges in moderate yields.