Antonella Guerriero, Mikael Erlandsson, A. Ienco
Mar 9, 2011
Citations
0
Influential Citations
14
Citations
Journal
Organometallics
Abstract
Reaction of (1,3,5-triaza-7-phosphaadamantane-6-yl)lithium (1; PTA-Li), synthesized in high yield and purity, with p-(dimethylamino)benzaldehyde gave the novel water-soluble β-phosphino alcohol (4′-(dimethylamino)phenyl)(1,3,5-triaza-7-phosphatricyclo[3.3.1.1]dec-6-yl)methanol (2; PZA-NMe2). The oxide O═PZA-NMe2 (3) and sulfide S═PZA-NMe2 (4) were also obtained. Ir(I) complexes of (SR,RS)-PZA-NMe2 and the analogue phenyl(1,3,5-triaza-7-phosphatricyclo[3.3.1.1]dec-6-yl)methanol (PZA) were obtained and used as precatalysts for the hydrogenation of α,β-unsaturated aldehydes and ketones and acetophenone using different mild reduction protocols. The X-ray crystal structure of the SR,RS diastereoisomer of PZA-NMe2 was also obtained and is described herein.