Guillaume Cantagrel, Benoît de Carné-Carnavalet, C. Meyer
Sep 9, 2009
Citations
0
Influential Citations
46
Citations
Journal
Organic letters
Abstract
Iron trichloride promotes the cationic cyclization of o-(arylethynyl)aryl isocyanates leading to 3-(arylchloromethylene)oxindoles which can be stereoselectively converted to (Z)-3-(aminomethylene)oxindoles under straightforward conditions. When the alkyne is substituted by an alkyl group, activation of the allylic C-H bond also occurs producing 1,2-(dichloroalkylidene)oxindoles.