T. Lane, B. D'Souza, J. Louie
Aug 14, 2012
Citations
0
Influential Citations
61
Citations
Journal
The Journal of organic chemistry
Abstract
Diynes and cyanamides undergo an iron-catalyzed [2 + 2 + 2] cycloaddition to form highly substituted 2-aminopyridines in an atom-efficient manner that is both high yielding and regioselective. This system was also used to cyclize two terminal alkynes and a cyanamide to afford a 2,4,6-trisubstituted pyridine product regioselectively.