P. Rushworth, D. G. Hulcoop, D. Fox
Sep 12, 2013
Citations
0
Influential Citations
25
Citations
Journal
The Journal of organic chemistry
Abstract
Tetramethylethylenediamine (TMEDA) acts as cheap and readily removed ligand in the iron-catalyzed coupling of alkyl Grignard reagents and activated aryl chlorides. The use of TMEDA allows for low ligand and iron catalyst loading as well as an increased reaction concentration and an ambient reaction temperature on a mole scale.