R. Mirzamatov, K. Lutfullin, V. M. Malikov
May 1, 1974
Citations
0
Influential Citations
1
Citations
Journal
Chemistry of Natural Compounds
Abstract
hyoscyamine [2]. In the NMR spec t rum of (I) (in CDC13, 6 scale, JNM 100/100 MHz, HMDS as internal standard) there is a singlet at 2.40 ppm (3 H, N-CH3) , two one-proton doublets at 5.65 and 6.15 ppm (C= CH2), a singlet at 7.22 ppm (5 H, monosubst i tuted benzene ring), a t r ip le t at 4.95 ppm (Call) and a singlet at 3.17 ppm (C6H and CTH). The molecu la r weight of ~I) determined m a s s s p e c t r o m e t r i c a l l y di f fers f r om that of hyoscine by 18 m/e . The facts given above, and also the absence of a depress ion of the melting point of a mix ture with an authentic sample shows that the base isolated is apohyoscine [3].