Kam Iu Leong, Paola F. Alviarez, R. Compagnone
Jun 1, 2009
Citations
1
Influential Citations
6
Citations
Journal
Pharmaceutical Biology
Abstract
The present work describes the phytochemical investigation of the aerial parts of Amanoa almerindae Leal (Euphorbiaceae). After fractionation of the organic extracts, four pentacyclic triterpenes (friedelin, lupeol, betulin, betulinic acid), three steroids (β-sitosterol, sitostenone, daucosterol), a lignan (49-demethyl- deoxypodophyllotoxin) and for first time in this genus the presence of the biflavones amentoflavone, sequoiaflavone, and putraflavone were identified. The structures of isolated compounds were established by spectroscopic methods and confirmed by comparison with reference samples and literature data. No previous phytochemical study of Amanoa almerindae has been reported, and to the best of our knowledge, this is the first report of biflavonoids in the Amanoa genus.