Michael G. Coleman, A. Hudson
2016
Citations
0
Influential Citations
4
Citations
Journal
Studies in natural products chemistry
Abstract
Abstract The biological diversity of natural products that contain a cyclopropane moiety is ubiquitous across the domains of life. One such naturally occurring compound that contains the cyclopropane moiety is 1-aminocyclopropane-1-carboxylic acid and its structural analogs. These compounds are of interest to the scientific community because they are endowed with a wide range of biological activities such as; antifungal, antimicrobial, antiviral, and antitumoral, among others. In this chapter, a compendium of research efforts centered on naturally occurring 1-aminocyclopropane-1-carboxylic acid moieties regarding their, (1) isolation from plants and microorganisms, (2) characterization using analytical and spectroscopic techniques, (3) strategies for their total synthesis, and (4) resultant biological activities will be discussed.