F. Shiau, R. Pandey, S. Ramaprasad
Mar 1, 1990
Citations
0
Influential Citations
17
Citations
Journal
Journal of Organic Chemistry
Abstract
Treatment of hematoporphyrin IX dimethyl ester (7) with tetrapropylammonium perruthenate (Pr{sup n}{sub 4}N)(RuO{sub 4}) and N-methylmorpholine N-oxide affords a high yield of the separable monoacetylmono(1-hydroxyethyl)-deuteroporphyrin isomers 5 and 6. Proton NMR NOE experiments and chemical transformations involving specific individual deuteration at the 1- and 3-methyls and 2- and 4-vinyls are used to characterize the isomers.