Siqing Peng, Faquan Yu, Danrui Xu
Aug 3, 2018
Citations
0
Influential Citations
3
Citations
Journal
Crystal Growth & Design
Abstract
Through structural modification of 2-anilinonicotinic acid by isomerization, a new synthon, acid-aminopyridine, is created, and the two original synthons, i.e., the acid–acid homosynthon and acid–pyridine heterosynthon are no longer observed in the newly designed 6-anilinonicotinic acids. The new synthon has a hydrogen-bond strength rivaling that of the acid–acid homosynthon and the acid–pyridine heterosynthon, as suggested by theoretical calculations, which explains its formation.