K. Taubert, S. Kraus, B. Schulze
Apr 1, 2002
Citations
0
Influential Citations
16
Citations
Journal
Sulfur Reports
Abstract
Abstract This review deals with methods for the synthesis, reactions and biological activity of isothiazol-3(2H)-ones. Monocyclic isothiazol-3(2H)-ones have been reported by oxidative cyclization of thiomalonamide derivatives, amides of 3-thionocarboxylic acids and 4,5-dithiaoctanediamides; by cyclocondensation of β-thiosubstituted propenamides and ring contraction of 1,4-thiazepines. Isothiazol-3(2H)-ones and their tautomer OH-forms have been investigated. Isothiazol-3(2H)-ones and their metal salt complexes are potent industrial microbiocides because of antifungal and antibacterial properties.