Adit Srivastava, A. Chandra, R. M. Singh
Feb 1, 2007
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0
Influential Citations
2
Citations
Journal
ChemInform
Abstract
A convenient synthesis of isothiazolo[5,4-b]quinolines 2 is achieved in two steps from the reaction of 2-chloro-3-formylquinolines 1 with sodium sulfide and hydroxylamine sequences followed by cyclisation with acetic anhydride. The subsequent oxidation of 2 with H 2 O 2 in acetic acid yields 3(2H)-one-1, 1-dioxideisothiazolo [5, 4-b] quinolines 3.