F. Cordero, A. Brandi, C. Querci
Mar 1, 1990
Citations
0
Influential Citations
41
Citations
Journal
Journal of Organic Chemistry
Abstract
Substituted five-membered cyclic nitrones cycloadd to substituted methylenecyclopropanes with high diastereofacial selectivity, through anti-anti transition states, to produce regioisomeric hexahydrospiro [cyclopropane-1,2'(and 3')-pyrrolol[1,2-b]isoxazolidines] 2-Spirocyclopropane derivatives undergo thermal rearrangement in mild conditions to 3,5-substituted indolizidinones by the regioselective cleavage of the cyclopropane ring leading to the more stabilized secondary radical