Xu Da
2002
Citations
0
Influential Citations
2
Citations
Journal
Chinese New Drugs Journal
Abstract
Itopride hydrochloride( itopride ) is a new gastrointestinal prokinetic agent.It regulated motility of the gastrointestinal tract through synergism of its dopamine D 2 receptor antagonistic action and its acetylcholine esterase inhibitory action.The concentrations of itopride in the brain were fairly low while it was distributed in the body.No evidence was found for its serious adverse reaction including its proarrhythmic effect.With data obtained from series of clinical study,it suggested that itopride could be a new choice of drug for treatment of gastroinestinal symptoms caused by reduced gastrointestinal motility in functional dyspepsia and chronic gastritis. [