V. Krasnov, G. Levit, I. N. Andreeva
2002
Citations
0
Influential Citations
32
Citations
Journal
Mendeleev Communications
Abstract
The acylation of racemic 2-methyl-1,2,3,4-tetrahydroquinoline and 2-methylindoline by (S)-naproxen acyl chloride resulted in their kinetic resolution with the predominant formation of (S,S)-diastereoisomeric amides (de78–76%), recrystallisation of which fol-lowed by acid hydrolysis gave individual (S)-isomers of heterocyclic amines.