F. Cantele, A. Restelli, S. Riva
Aug 1, 2001
Citations
0
Influential Citations
6
Citations
Journal
Advanced Synthesis & Catalysis
Abstract
Kinetic resolution of racemic methyl trans-3-(4-methoxyphenyl)glycidate, a key intermediate for the synthesis of the well-known drug diltiazem hydrochloride, has been accomplished by transesterification reactions with suitable amino alcohols catalyzed by Novozym 435 in organic solvents.