Hitoshi Tanaka, T. Suzuka, Kazuya Hada
May 15, 2000
Citations
0
Influential Citations
10
Citations
Journal
Polymer Journal
Abstract
Radical polymerization of captodative (cd) substituted 2-acetamidoacrylic acid (1) was studied kinetically at 40°C. The rate constants of propagation (kp) and termination (kt) of 1 were estimated by a rotating sector and an inhibitor method using 1,3,5-triphenylverdazyl. Termination was depressed and kp/kt became high, which was responsible for the high radical polymerization reactivity of 1 in spite of the cd olefin. The hydrogel consisting of poly(acetyl dehydroalanine) network was synthesized by the copolymerization of 1 and bifunctional cross-linker with the structure analogous to 1. The swelling ratio of the gel was dependent on the cross-linker concentration and reached a maximum of 1334 at 2% cross-linker concentration in the feed. The gel showed stimuli-responce to pH and electric field, i.e., the gel volume increased to twice as much when transferred from an acidic solution into an alkaline solution and the gel bent toward an anode side within a few minutes when the electric field was applied. Biodegradability of the polymers was examined using α-chymotrypsin.