R. Fager, P. Gentilcore, E. W. Abrahamson
Dec 31, 1978
Citations
0
Influential Citations
7
Citations
Journal
Vision Research
Abstract
Abstract Sodium cyanoborohydride reduces bovine rhodopsin's chromophore. The linear dependence of the kinetics on reductant concentration and the pH and temperature dependence of the reaction are evidence for penetration into the hydrophobic pocket of the native molecule. This supports earlier work indicating a Schiffs base linkage between the retinal chromophore and a lysine in the peptide chain.