M. Khan
2003
Citations
0
Influential Citations
1
Citations
Journal
International Journal of Chemical Kinetics
Abstract
The rate of cleavage of ethyl N-[o-(N-methyl-N-hydroxycarbamoyl)benzoyl]- carbamate (ENMBC) in the buffer solutions containing N-methylhydroxylamine, acetate + N-methylhydroxylamine, and phosphate + N-methylhydroxylamine followed an irreversible consecutive reaction path: ENMBC where A and B represent N-hydroxyl group cyclized product of ENMBC and o-(N-methyl-N-hydroxycarbamoyl)benzoic acid, respectively. Both rate constants k1 obs and k2 obs showed the presence of buffer catalysis, but buffer catalysis turned out to be weak in the presence N-methylhydroxylamine buffer, while it was strong in the presence of acetate and phosphate ones. Buffer-independent rate constants k10 and k20 increased linearly with the increase in aOH with definite intercepts. The values of molar absorption coefficient of A, obtained under varying total buffer concentrations at a constant pH, showed the presence of a fast equilibrium: A + CH3NHOH ⇆ C, where C represents N-[o-(N-methyl-N-hydroxycarbamoyl)methyl]benzohydroxamic acid. © 2003 Wiley Periodicals, Inc. Int J Chem Kinet 35: 427–437, 2003